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Antiplatelet Class

Abciximab

Brand: ReoPro (US/EU) / Abcixirel (IN) / Abximab (IN) / Reopro (BD)
Subclass: GP IIb/IIIa inhibitor (IV, monoclonal antibody)
PK: t½ 0.5 hours | Clearance: hepatic
severe
AE: Bleeding, thrombocytopenia, hypotension, allergic reactions

Aspirin

Brand: Ecosprin / Ascard
Subclass: COX-1 inhibitor (irreversible)
PK: t½ 3 hours | Clearance: hepatic
Max Dose: 4000 day
severe
AE: GI irritation, dyspepsia, gastritis, peptic ulcer/bleeding risk, renal impairment (dose-dependent), tinnitus at toxic levels, metabolic acidosis in overdose, Reye's syndrome r…

Cangrelor

Brand: Kengreal (US/EU) / Cangrelor (IN) / Kengreal (BD)
Subclass: P2Y12 inhibitor (IV, reversible, rapid onset)
PK: t½ 0.1 hours | Clearance: other
moderate
AE: Bleeding, hypotension, dyspnea

Cilostazol

Brand: Pletal (US/EU) / Cilacar (IN) / Cilodoc (IN) / Cilosta (BD)
Subclass: PDE-III inhibitor (antiplatelet + vasodilator)
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 200 day
moderate
AE: Headache, palpitations, tachycardia, edema, diarrhea

Clopidogrel

Brand: Plavix (US/EU) / Clopitab (IN) / Clopivas (IN) / Clopid (BD)
Subclass: P2Y12 inhibitor (thienopyridine, prodrug)
PK: t½ 8 hours | Clearance: hepatic
Max Dose: 600 day
moderate
AE: Bleeding (GI/intracranial), dyspepsia, rash; RARE: thrombotic thrombocytopenic purpura (TTP), neutropenia

Dipyridamole

Brand: Persantine (US/EU) / Pdyl (IN) / Aggrenox-combo (BD)
Subclass: PDE inhibitor (vasodilatory antiplatelet)
PK: t½ 10 hours | Clearance: hepatic
Max Dose: 400 day
mild
AE: Headache, flushing, hypotension, dizziness, GI upset

Eptifibatide

Brand: Integrilin (US/EU) / Eptifiban (IN) / Eptif (BD)
Subclass: GP IIb/IIIa inhibitor (IV, cyclic peptide)
PK: t½ 2.5 hours | Clearance: renal
moderate
AE: Bleeding, thrombocytopenia, hypotension, back pain

Prasugrel

Brand: Effient (US/EU) / Prasita (IN) / Prasurel (IN) / Prasugrel (BD)
Subclass: P2Y12 inhibitor (irreversible, prodrug)
PK: t½ 7 hours | Clearance: hepatic
Max Dose: 10 day
severe
AE: Bleeding (higher risk than clopidogrel), easy bruising, anemia

Ticagrelor

Brand: Brilinta (US/EU) / Ticawell (IN) / Ticaflo (IN) / Ticadro (BD)
Subclass: P2Y12 inhibitor (reversible, not a prodrug)
PK: t½ 7 hours | Clearance: hepatic
Max Dose: 180 day

Tirofiban

Brand: Aggrastat (US/EU) / Aggril (IN) / Tirof (BD)
Subclass: GP IIb/IIIa inhibitor (IV, small-molecule)
PK: t½ 2 hours | Clearance: renal
moderate
AE: Bleeding, thrombocytopenia, hypotension