Antianginal Class
Isosorbide Dinitrate
Brand: Isordil (US/EU) / Sorbitrate (IN) / Isodinit (BD)
Subclass: Organic nitrate vasodilator
PK:
t½ 1 hours | Clearance: hepatic
Max Dose: 120 day
Max Dose: 120 day
moderate
AE: Headache, hypotension, flushing, syncope, reflex tachycardia
AE: Headache, hypotension, flushing, syncope, reflex tachycardia
Isosorbide Mononitrate
Brand: Monoket (US/EU) / Imdur (US/EU) / Monotrate (IN) / Isomack (BD)
Subclass: Organic nitrate vasodilator
PK:
t½ 5 hours | Clearance: hepatic
Max Dose: 120 day
Max Dose: 120 day
moderate
AE: Headache, hypotension, dizziness, flushing, syncope
AE: Headache, hypotension, dizziness, flushing, syncope
Nitroglycerin
Brand: Nitrostat (US/EU) / Angised (IN) / Nitroglycerin (BD)
Subclass: Organic nitrate vasodilator
PK:
t½ 0.3 hours | Clearance: hepatic
Max Dose: 15 day
Max Dose: 15 day
moderate
AE: Headache, flushing, hypotension, reflex tachycardia, dizziness, syncope
AE: Headache, flushing, hypotension, reflex tachycardia, dizziness, syncope
Ranolazine
Brand: Ranexa (US/EU) / Ranozex (IN) / Ranolaz (BD)
Subclass: Late sodium-current inhibitor
PK:
t½ 7 hours | Clearance: hepatic
Max Dose: 1000 day
Max Dose: 1000 day
moderate
AE: Dizziness, constipation, nausea, headache, QT interval prolongation
AE: Dizziness, constipation, nausea, headache, QT interval prolongation