Categories

All Analgesic Analgesic Combination Antianginal Antibiotic Anticancer Anticoagulant Anticonvulsant Antidepressant Antidiabetic Antidiarrheal Antihypertensive Antimalarial Antiparasitic Antiparkinson Antiplatelet Antipsychotic Anxiolytic Bronchodilator Cardiovascular Corticosteroid Diuretic Emergency Endocrine Gastrointestinal Immunomodulator Immunosuppressant Minerals Neurological NSAID Oncology – Targeted therapy Psychiatric Sedative/Hypnotic Sympathomimetic Vitamins

Antidiabetic Class

Canagliflozin

Brand: Invokana (US/EU) / Cana (IN/BD)
Subclass: SGLT2 inhibitor
PK: t½ 12 hours | Clearance: mixed
Max Dose: 300 day
moderate
AE: Genital mycotic infection, polyuria, volume depletion, euglycemic DKA (rare), ↑fracture/amputation signal

Dapagliflozin

Brand: Farxiga (US/EU) / Forxiga (EU) / Dapa (IN/BD)
Subclass: SGLT2 inhibitor
PK: t½ 12 hours | Clearance: mixed
Max Dose: 10 day
moderate
AE: Genital mycotic infections, polyuria, volume depletion, rare euglycemic DKA

Dulaglutide

Brand: Trulicity
Subclass: GLP-1 receptor agonist (once-weekly)
PK: t½ 5 days | Clearance: other
Max Dose: 4.5 week
moderate
AE: Nausea, vomiting, diarrhea, abdominal pain, decreased appetite

Empagliflozin

Brand: Jardiance (US/EU) / Empa (IN) / Empaglo (BD)
Subclass: SGLT2 inhibitor
PK: t½ 12 hours | Clearance: mixed
Max Dose: 25 day
moderate
AE: Genital mycotic infections, polyuria, volume depletion, rare euglycemic DKA

Ertugliflozin

Brand: Steglatro (US/EU)
Subclass: SGLT2 inhibitor
PK: t½ 17 hours | Clearance: mixed
Max Dose: 15 day
moderate
AE: Genital infections, polyuria, dehydration, euglycemic DKA (rare)

Exenatide

Brand: Byetta (BID) / Bydureon (weekly ER)
Subclass: GLP-1 receptor agonist
PK: t½ 2.4 hours | Clearance: renal
Max Dose: 20 day
moderate
AE: Nausea, vomiting, diarrhea, headache; injection-site reactions (ER)

Glibenclamide

Brand: Glynase (US) / Daonil (IN) / Glybenta (BD)
Subclass: Sulfonylurea (insulin secretagogue)
PK: t½ 10 hours | Clearance: hepatic
Max Dose: 10 day
severe
AE: Severe hypoglycemia, weight gain, dizziness

Gliclazide

Brand: Diamicron (US/EU) / Glynase (IN) / Gliclade (BD)
Subclass: Sulfonylurea (insulin secretagogue)
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 320 day
moderate
AE: Hypoglycemia, weight gain, rash (rare)

Glipizide

Brand: Glucotrol (US) / Glip (IN) / Gliplon (BD)
Subclass: Sulfonylurea (insulin secretagogue)
PK: t½ 2.5 hours | Clearance: hepatic
Max Dose: 40 day
moderate
AE: Hypoglycemia, weight gain, dizziness, rash

Insulin Degludec

Brand: Tresiba (US/EU)
Subclass: Ultra-long basal insulin
PK: t½ 25 hours | Clearance: other
severe
AE: Hypoglycemia, weight gain, injection-site reactions

Insulin Detemir U100

Brand: Levemir (US/EU)
Subclass: Basal insulin (long-acting)
PK: t½ 12 hours | Clearance: other
severe
AE: Hypoglycemia, weight gain, injection-site reactions

Insulin Glargine U100

Brand: Lantus (US/EU) / Basalog (IN) / Basugine (BD)
Subclass: Basal insulin (long-acting)
PK: t½ 12 hours | Clearance: other
severe
AE: Hypoglycemia, weight gain, lipodystrophy at injection site

Linagliptin

Brand: Tradjenta (US/EU) / Trajenta (IN) / Linapta (BD)
Subclass: DPP-4 inhibitor
PK: t½ 12 hours | Clearance: hepatic
Max Dose: 5 day
mild
AE: Nasopharyngitis, cough, rare pancreatitis, joint pain

Liraglutide

Brand: Victoza (T2DM) / Saxenda (Weight loss)
Subclass: GLP-1 receptor agonist
PK: t½ 13 hours | Clearance: other
Max Dose: 1.8 day
moderate
AE: Nausea, vomiting, diarrhea/constipation, decreased appetite, injection-site reactions

Lixisenatide

Brand: Adlyxin / Lyxumia
Subclass: GLP-1 receptor agonist (once-daily)
PK: t½ 3 hours | Clearance: renal
Max Dose: 20 day
moderate
AE: Nausea, vomiting, diarrhea, dizziness, headache

Metformin

Brand: Glucophage / Glycomet (IN) / Diabetmin (BD)
Subclass: Biguanide
PK: t½ 6 hours | Clearance: renal
Max Dose: 2550 day
moderate
AE: Gastrointestinal upset (nausea, diarrhea, metallic taste), B12 deficiency with long-term use, RARE: lactic acidosis (risk in renal/hepatic/cardiac failure)

Pioglitazone

Brand: Actos (US/EU) / Pioz (IN) / Piobet (BD)
Subclass: Thiazolidinedione (PPAR-γ agonist)
PK: t½ 7 hours | Clearance: hepatic
Max Dose: 45 day
moderate
AE: Weight gain, edema, fractures in women, rare bladder cancer risk

Semaglutide

Brand: Ozempic (US/EU) / Rybelsus (oral) / Semaglu (IN/BD)
Subclass: GLP-1 receptor agonist (incretin mimetic)
PK: t½ 160 hours | Clearance: other
Max Dose: 2 week
moderate
AE: Nausea, vomiting, diarrhea, risk of gallbladder disease; rare pancreatitis

Sitagliptin

Brand: Januvia (US/EU) / Istavel (IN) / Sitazid (BD)
Subclass: DPP-4 inhibitor
PK: t½ 12 hours | Clearance: renal
Max Dose: 100 day
mild
AE: Nasopharyngitis, headache, rare pancreatitis, joint pain

Teneligliptin

Brand: Tenepure/Tenepride (IN/BD)
Subclass: DPP-4 inhibitor
PK: t½ 24 hours | Clearance: hepatic
Max Dose: 40 day
mild
AE: Nasopharyngitis, mild GI upset, rare hepatic enzyme elevation

Tirzepatide

Brand: Mounjaro (US/EU) / Zepbound (US)
Subclass: Dual GIP and GLP-1 receptor agonist
PK: t½ 120 hours | Clearance: other
Max Dose: 15 week
moderate
AE: Nausea, vomiting, diarrhea, decreased appetite, delayed gastric emptying

Vildagliptin

Brand: Galvus (EU/IN) / Vilda (BD)
Subclass: DPP-4 inhibitor
PK: t½ 3 hours | Clearance: mixed
Max Dose: 100 day
mild
AE: Nasopharyngitis, headache, rare hepatic enzyme rise