pk.drugs – Detail
← Back

Meloxicam

Brand: Mobic (global) / Melocam, Meloxic (IN/BD)
NSAID Oxicam derivative (preferential COX-2 inhibitor)

Chemistry

Molecular Formula C14H13N3O4S2
PubChem CID: 54675776
Open in PubChem
Structure
structure

Pharmacokinetics

Half-life 20 hours
Clearance Route hepatic
Active Metabolites minor
Notes COX-2 preferential; safer GI profile vs. piroxicam; avoid in renal impairment and volume depletion.

⚠️ Safety & Warnings

Severity: Moderate

Adverse Effects:
Dyspepsia, nausea, edema, increased BP, renal impairment; rare SJS/TEN

Contraindications:
Active GI ulcer/bleed, NSAID hypersensitivity, severe renal/hepatic failure, late pregnancy

Precautions:
Monitor BP, renal function; avoid combination with other NSAIDs; caution in elderly