Paromomycin
Brand: Humatin / Paromomycin (generic)
Antiparasitic
Aminoglycoside antiprotozoal (non-absorbed)
Pharmacokinetics
| Half-life | 6 hours |
| Clearance Route | mixed |
| Active Metabolites | none |
| Notes | Minimal systemic absorption; safe in pregnancy for amoebiasis. |
⚠️ Safety & Warnings
Severity: Mild
Adverse Effects:
GI upset, cramps; systemic toxicity rare
Contraindications:
Intestinal obstruction (avoid)
Precautions:
Caution in ulcerative lesions of gut (increased absorption risk)