Indapamide

Brand: Natrilix / Lozol

Diuretic Thiazide-like diuretic

Chemistry

Molecular Formula	C16H16ClN3O3S
PubChem	CID: 3716 Open in PubChem

Structure

Half-life	16 hours
Clearance Route	hepatic
Active Metabolites	yes
Notes	Long duration; minimal electrolyte disturbance compared to HCTZ.

Severity: Moderate

Adverse Effects:
Hyponatremia, hypokalemia, dizziness

Contraindications:
Severe renal impairment, sulfonamide allergy

Precautions:
Monitor Na⁺/K⁺ periodically; caution in elderly