Epirubicin
Brand: Ellence (global)
Anticancer
Anthracycline (topoisomerase II inhibitor)
Pharmacokinetics
| Half-life | 30 hours |
| Clearance Route | hepatic |
| Active Metabolites | yes |
| Notes | Less cardiotoxic than doxorubicin, but lifetime cumulative dose limit still applies. |
⚠️ Safety & Warnings
Severity: Life-threatening
Adverse Effects:
Myelosuppression, cardiotoxicity, mucositis, alopecia
Contraindications:
Severe cardiac dysfunction
Precautions:
Monitor cardiac EF; cumulative dose limit must be respected