Pitavastatin
Brand: Livalo (US/EU) / Pivasta (IN) / Pitava (JP)
Cardiovascular
Statin (HMG-CoA reductase inhibitor)
Pharmacokinetics
| Half-life | 12 hours |
| Tmax | 1 h |
| Bioavailability | 60 % (approx) |
| Protein Binding | 99 % |
| Volume of Distribution | 0.2 L/kg (approx) |
| Clearance Route | hepatic |
| Active Metabolites | no |
| Notes | Does not worsen HbA1c like atorvastatin; good option in diabetic dyslipidemia. |
⚠️ Safety & Warnings
Severity: Mild
Adverse Effects:
Myalgia, mild liver enzyme elevation
Contraindications:
Pregnancy, active liver disease
Precautions:
Good choice in diabetics; use low dose in Asian ethnicity