Roxithromycin
Brand: Roxid (IN) / Roxim (BD)
Antibiotic
Macrolide
Pharmacokinetics
| Half-life | 12 hours |
| Tmax | 2 h |
| Bioavailability | 50 % (approx) |
| Protein Binding | 95 % |
| Volume of Distribution | 0.3 L/kg (approx) |
| Clearance Route | hepatic |
| Active Metabolites | no |
| Notes | Common dosing 150 mg bid or 300 mg od. |
⚠️ Safety & Warnings
Severity: Moderate
Adverse Effects:
GI upset, mild QT prolongation
Contraindications:
Significant hepatic impairment
Precautions:
Caution in patients on other QT prolonging medications