Cefalexin
Brand: Keflex (US/EU) / Cefakind (IN) / Cefalexin (BD)
Antibiotic
Cephalosporin 1st generation
Pharmacokinetics
| Half-life | 1 hours |
| Tmax | 1 h |
| Bioavailability | 90 % (approx) |
| Protein Binding | 10 % |
| Volume of Distribution | 0.2 L/kg (approx) |
| Clearance Route | renal |
| Active Metabolites | no |
| Notes | Most commonly dosed 500 mg q6–8h. |
⚠️ Safety & Warnings
Severity: Mild
Adverse Effects:
GI upset, rash, diarrhea
Contraindications:
Immediate penicillin anaphylaxis
Precautions:
Cross-reactivity with penicillin allergy low but caution if true anaphylaxis history