Pomalidomide
Brand: Pomalyst (global)
Anticancer
Immunomodulatory agent (IMiD)
Pharmacokinetics
| Half-life | 7.5 hours |
| Clearance Route | hepatic |
| Active Metabolites | no |
| Notes | High potency IMiD; less neuropathy vs thalidomide; thrombosis prophylaxis recommended. |
⚠️ Safety & Warnings
Severity: Severe
Adverse Effects:
Myelosuppression, fatigue, thrombosis risk, rash
Contraindications:
Pregnancy
Precautions:
Prevent pregnancy; consider anticoagulation prophylaxis when combined with dexamethasone