| Half-life | 3 hours |
| Clearance Route | renal |
| Active Metabolites | no |
| Notes | Dose must be reduced in renal impairment; thrombosis prophylaxis often required if combined with steroids. |
Severity: Severe
Adverse Effects:
Myelosuppression, thrombosis, fatigue, rash
Contraindications:
Pregnancy
Precautions:
Avoid pregnancy; thromboprophylaxis advised when combined with dexamethasone