Ceftaroline

Brand: Teflaro (US/EU)

Antibiotic Cephalosporin 5th generation (MRSA active)

Chemistry

Molecular Formula	C22H21N8O8PS4
PubChem	CID: 10184639 Open in PubChem

Structure

Half-life	2.6 hours
Tmax	1 h
Bioavailability	100 % (approx)
Protein Binding	20 %
Volume of Distribution	0.3 L/kg (approx)
Clearance Route	renal
Active Metabolites	no
Notes	Typical dose 600 mg IV q12h (adjust for renal impairment).

Severity: Moderate

Adverse Effects:
GI upset, neutropenia, rash

Contraindications:
Immediate beta-lactam anaphylaxis

Precautions:
CBC monitoring recommended if prolonged therapy