Citicoline

Brand: CDP-Choline / Citicoline (various)

Neurological Neuroprotective / cholinergic precursor

Chemistry

Molecular Formula	C14H26N4O11P2
PubChem	CID: 13804 Open in PubChem

Structure

Half-life	56 hours
Tmax	1 h
Clearance Route	renal
Active Metabolites	yes
Notes	Leaflet reports long elimination half-life (CO2/urine). PK varies by formulation; confirm local product insert.

Severity: Mild

Adverse Effects:
Headache, insomnia, nausea, diarrhea; rarely hypotension

Contraindications:
Hypersensitivity to citicoline (per local label)

Precautions:
Use caution if significant insomnia/anxiety; confirm pregnancy/lactation guidance from local product insert