Chlorthalidone

Brand: Hygroton / Thalitone

Diuretic Thiazide-like diuretic

Chemistry

Molecular Formula	C14H11ClN2O4S2
PubChem	CID: 2732 Open in PubChem

Structure

Half-life	50 hours
Clearance Route	renal
Active Metabolites	no
Notes	Extremely long half-life; preferred for hypertension.

Severity: Moderate

Adverse Effects:
Hyponatremia, hypokalemia, hyperuricemia

Contraindications:
Anuria, sulfonamide allergy

Precautions:
Monitor electrolytes; caution in gout and elderly