Rasagiline

Brand: Azilect (US/EU) / Rasagin (IN) / Rasact (BD)

Antiparkinson MAO-B inhibitor

Chemistry

Molecular Formula	C12H13N
PubChem	CID: 3034151 Open in PubChem

Structure

Half-life	7 hours
Tmax	1 h
Bioavailability	36 % (approx)
Protein Binding	60 %
Volume of Distribution	1.5 L/kg (approx)
Clearance Route	hepatic
Active Metabolites	no
Notes	No amphetamine-like metabolites; preferred over selegiline for tolerability.

Severity: Moderate

Adverse Effects:
Headache, arthralgia, depression, nausea

Contraindications:
Use with other MAO inhibitors; serotonergic agents may cause serotonin syndrome

Precautions:
Avoid severe tyramine overload; monitor for serotonin syndrome if combined with antidepressants